博士論文 / 近藤崇伸 / Nagasaki University (長崎大学) / 博士(歯学)

近藤崇伸

Objective: To investigate how types of tooth movement, bodily or tipping, influence the displacement of the center of resistance in teeth and alveolar bone resorption. Materials and Methods: Ten-week-old female Wistar rats were divided into eight groups of different factors, as follows: type of movement (bodily and tip...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第951号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

江頭寿洋

Bone marrow concentrate (BMC), which is enriched in mononuclear cells (MNCs) and platelets, has recently attracted the attention of clinicians as a new optional means for bone engineering. We previously reported that the osteoinductive effect of bone morphogenetic protein-2 (BMP-2) could be enhanced synergistically by ...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第1022号 / 2018-03-07

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

稲葉菜緒

Osteocytes play important roles in controlling bone quality as well as preferential alignment of biological apatite c-axis/collagen fibers. However, the relationship between osteocytes and mechanical stress remains unclear due to the difficulty of three-dimensional (3D) culture of osteocytes in vitro. The aim of this s...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第991号 / 2017-09-06

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

井口聡

Objective: The purpose of the present study was to examine the effects of a Polyglycolic acid (PGA) sheet with fibrin glue in the prevention of scar shrinkage. Methods: A PGA sheet with fibrin glue was grafted into the tongue after partial glossectomy in 25 rabbits. The wounds were examined histologically and compared ...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第992号 / 2017-09-06

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

品川兼一

The effect inflammation has on cancer prognosis is marked by the presence of cytokines and chemokines. Interleukin-6 (IL-6) is one a multifunctional cytokine that regulates inflammatory responses. We investigated the roles of IL-6 and STAT3 and examined the relationship between IL-6 signaling and clinicopathological fa...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第921号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

大久保賢亮

The present study was designed to investigate the relationships between clinicopathological findings and the resorptive conditions of root apices of teeth with periodontitis. The samples included 21 root apices with large periapical radiolucent lesions. The preoperative computed tomography (CT) and intraoperative findi...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第906号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

林田咲

Background: One of the main causes of ventilator-associated pneumonia (VAP) is thought to be aspiration of oropharyngeal fluid containing pathogenic microorganisms. The aim of this study was to examine the effects of various oral care methods on the reduction of oral bacteria during intubation. Methods: First, the effe...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第922号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

森下廣太

Foreign body giant cells (FBGCs) and osteoclasts are multinucleated giant cells (MNGCs), both of which are formed by the fusion of macrophage-derived mononuclear cells. Osteoclasts are distinct from FBGCs due to their bone resorption ability; however, not only morphological, but also functional similarities may exist b...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第923号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

Montenegro Raudales Jorge Luis

Dental calculus is a mineralized deposit associated with periodontitis. The bacterial components contained in dental calculus can be recognized by host immune sensors, such as Toll-like receptors (TLRs), and induce transcription of proinflammatory cytokines, such as IL-1β. Studies have shown that cellular uptake of cry...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第907号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

財津有未

Recent studies have shown that infection with Porphyromonas gingivalis, a major periodontal pathogen, hastens the progression of non-alcoholic fatty liver disease (NAFLD). However, the intracellular fate of P. gingivalis in hepatocytes remains unknown. Here, using oleic-acid-induced HepG2 cells as an in vitro model for...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第916号 / 2017-03-21

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

中谷佑哉

Objective: Platelet-rich plasma (PRP) is typically isolated and applied immediately after preparation, making it both a time- and labor-intensive addition to the operative procedure. Thus, it would be convenient if PRP could be preserved. We evaluated the efficacy of freeze-dried PRP (FD-PRP), as compared with freshly ...

Nagasaki University (長崎大学) / 博士(歯学) / 甲医歯薬第913号 / 2017-02-01

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

Harrell Daniel Toshio

Background: Short QT syndrome (SQTS) is a rare inheritable arrhythmia, associated with atrial and ventricular fibrillations, caused by mutations in six cardiac ion channel genes with high penetrance. However, genotype-specific clinical differences between SQTS patients remain to be elucidated. Methods and results: We s...

Nagasaki University (長崎大学) / 博士(医学) / 甲医歯薬第1009号 / 2018-03-31

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

荻原久美

Background: 5-Aminolevulinic acid is a precursor of photosensitizing protoporphyrin IX and has been applied for photodynamic diagnosis of brain and bladder tumors with few side effects. Although most upper gastrointestinal tumors can be detected during photodynamic diagnosis, some tumors containing signet-ring cells ca...

Nagasaki University (長崎大学) / 博士(医学) / 甲医歯薬第1039号 / 2018-03-20

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

野口智恵子

Background: Surgical-site infections due to intraoperative contamination are chiefly ascribable to airborne particles carrying microorganisms. The purpose of this study is to identify the actions that increase the number of airborne particles in the operating room. Methods: Two surgeons and two surgical nurses performe...

Nagasaki University (長崎大学) / 博士(医学) / 甲医歯薬第1037号 / 2018-03-20

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

小屋松淳

Background: Although we reported in a previous study that diabetes with a high serum triglycerides to high-density lipoprotein cholesterol (TG-HDL) ratio constitutes a risk for atherosclerosis, associations in terms of TG-HDL ratio between diabetes and gamma-glutamyltransferase (GGT), which is also known as an independ...

Nagasaki University (長崎大学) / 博士(医学) / 甲医歯薬第1034号 / 2018-03-20

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

山島美緒

Sarcopenia has been reported to be associated with the prognosis of patients with liver cirrhosis and hepatocellular carcinoma (HCC). The aim of the present study was to determine whether sarcopenia was associated with the prognosis of patients with HCC treated with sorafenib. A total of 40 patients with HCC who were t...

Nagasaki University (長崎大学) / 博士(医学) / 甲医歯薬第1040号 / 2018-03-20

機関リポジトリ (長崎大学) 機関リポジトリ (長崎大学) NDLデジタルコレクション

Matsumoto Ayako / Kajiya Hiroshi / YamamotoM Nana / Yanagi Tsukasa / Imamura Ayaka / Okabe Koji / Fukushima Tadao / Kido Hirofumi / Ohno Jun

Scaffolds implanted into bone defect sites must achieve optimal biodegradation rates while appropriately filling the void as new bone formation progresses. We recently developed a unique biomaterial consisting of salmon deoxyribose nucleic acid (DNA) and protamine, which can be used as an osteoconductive scaffold for t...

福岡歯科大学 / 博士（歯学） / 甲第296号 / 2018-03-29

機関リポジトリ (福岡歯科大学) NDLデジタルコレクション

Ogata Kayoko / Tsumuraya Tomoyuki / Oka Kyoko / Shin Masashi / Okamoto Fujio / Kajiya Hiroshi / Katagiri Chiaki / Ozaki Masao / Matsushita Masayuki / Okabe Koji

Transient receptor potential melastatin-7 (TRPM7) is a bi-functional protein containing a kinase domain fused to an ion channel. TRPM7 is highly expressed in ameloblasts during tooth development. Here we show that TRPM7 kinase-inactive knock-in mutant mice (TRPM7 KR mice) exhibited small enamel volume with opaque white...

福岡歯科大学 / 博士（歯学） / 甲第297号 / 2018-03-29

機関リポジトリ (福岡歯科大学) NDLデジタルコレクション

中辻和樹

岡山大学 / 博士（歯学） / 甲第5709号 / 2018-03-23

機関リポジトリ (岡山大学) NDLデジタルコレクション

松原理紗

岡山大学 / 博士（歯学） / 甲第5700号 / 2018-03-23

機関リポジトリ (岡山大学) NDLデジタルコレクション

福島麻衣

岡山大学 / 博士（歯学） / 甲第5710号 / 2018-03-23

機関リポジトリ (岡山大学) NDLデジタルコレクション