【博士論文】学術データベース

博士論文 / Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits 麻酔下ウサギにおいて末梢および中枢性嚥下が顎反射に及ぼす影響

著者

書誌事項

タイトル

Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits

タイトル別名

麻酔下ウサギにおいて末梢および中枢性嚥下が顎反射に及ぼす影響

著者名

Suzuki Taku

著者名

鈴木拓

学位授与大学

新潟大学 (大学ID:0035) (CAT機関ID:KI000356)

取得学位

博士(歯学)

学位授与番号

甲第4504号

学位授与年月日

2018-09-20

注記・抄録

学位の種類: 博士(歯学). 報告番号: 甲第4504号. 学位記番号: 新大院博(歯)甲第412号. 学位授与年月日: 平成30年9月20日

This study aimed to investigate whether the jaw-opening (JOR) and jaw-closing reflexes (JCR) are modulated during not only peripherally, but also centrally, evoked swallowing. Experiments were carried out on 24 adult male Japanese white rabbits. JORs were evoked by trigeminal stimulation at 1 Hz for 30 s. In the middle 10 s, either the superior laryngeal nerve (SLN) or cortical swallowing area (Cx) was simultaneously stimulated to evoke swallowing. The peak-to-peak JOR amplitude was reduced during the middle and late 10-s periods (i.e., during and after SLN or Cx stimulation), and the reduction was dependent on the current intensity of SLN/Cx stimulation: greater SLN/Cx stimulus current resulted in greater JOR inhibition. The reduction rate was significantly greater during Cx stimulation than during SLN stimulation. The amplitude returned to baseline 2 min after 10-s SLN/Cx stimulation. The effect of co-stimulation of SLN and Cx was significantly greater than that of SLN stimulation alone. There were no significant differences in any parameters of the JCR between conditions. These results clearly showed that JOR responses were significantly suppressed, not only during peripherally evoked swallowing but also during centrally evoked swallowing, and that the inhibitory effect is likely to be larger during centrally compared with peripherally evoked swallowing. The functional implications of these results are discussed.

元資料の権利情報 : (C) 2018 Elsevier B.V. All rights reserved.

キーワード

swallow, superior laryngeal nerve, Rabbit, Jaw-opening reflex, Jaw-closing reflex, Cortical swallowing area

各種コード

NII論文ID(NAID)

500001084890

NII著者ID(NRID)
  • 8000001208595
  • 8000001208596
DOI (出版社)

10.1016/j.brainres.2018.05.002

DOI

info:doi/10.1016/j.brainres.2018.05.002

本文言語コード

eng

データ提供元

機関リポジトリ / NDLデジタルコレクション

DOI

博士論文 / 新潟大学 / 歯学

博士論文 / 新潟大学

博士論文 / 歯学

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