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博士論文 / Dual Energy CTを用いた正常乳腺組織と腫瘍組織の評価 Evaluation of normal breast tissue and tumor tissue by using Dual Energy CT

著者

書誌事項

タイトル

Dual Energy CTを用いた正常乳腺組織と腫瘍組織の評価

タイトル別名

Evaluation of normal breast tissue and tumor tissue by using Dual Energy CT

著者名

金行由樹子

学位授与大学

弘前大学 (大学ID:0008) (CAT機関ID:KI000083)

取得学位

博士(保健学)

学位授与番号

甲第064号

学位授与年月日

2017-03-23

注記・抄録

The present study aimed to investigate the possibility of using dual-energy computed tomography (DECT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. The following patient data were extracted by interview and from the hospital’s radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the core needle biopsy. The median age of the 43 participants was 56 years (range, 30 -80 years). The CT values were evaluated using a clinical analytical program based on the three-material decomposition technique. Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of DECT in the diagnosis of breast cancer. By contrast, DECT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourages the development of DECT imaging to improve tumor detection in patients with breast cancer.

キーワード

乳腺, CT, 腫瘍

各種コード

NII論文ID(NAID)

500001033767

NII著者ID(NRID)
  • 8000001135170
本文言語コード

ja

データ提供元

機関リポジトリ / NDLデジタルコレクション

外部リンク

博士論文 / 弘前大学 / 保健学

博士論文 / 弘前大学

博士論文 / 保健学

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